Bioactive Small Molecules
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Filtered Search Results
Cayman Chemical ANTIBODY ZIdovudIn 100mg
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An NRTI; reduces HIV-1 p24 antigen levels in the culture supernatant of HIV-1-infected isolated human peripheral blood monocytes at 0.01, 0.1, and 1 µM
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Cayman Chemical ANTIBODY TIcagrelor 25mg
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A reversible purinergic P2Y12 receptor antagonist (Ki = 14 nM; IC50 = 1.8 μM)
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Cayman Chemical ANTIBODY XL019 25mg
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A potent, bioavailable JAK inhibitor with preference for JAK2 (IC50 = 2 nM) over JAK1 and JAK3 (IC50s = 130 and 250 nM, respectively); effective against JAK2V617F as well as JAK2 and inhibits phosphorylation of STAT5 in vivo
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Cayman Chemical ANTIBODY R-7050 5mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A cell-permeable antagonist of signaling through the TNF-α receptor complex (EC50 = 0.631 µM), blocking TNF-α-induced binding of TNF-α receptor I with TRADD and RIP1
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Cayman Chemical N1 N12-DIacetylspermInhydr 5mg
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A diacetylated derivative of spermine that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine; used as a biomarker for cancer detection
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Cayman Chemical ANTIBODY LucIgenIn 500mg
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A chemiluminescent probe; used to detect superoxide production by enzymatic and cellular sources; produces similar chemiluminescence in isolated aortic and cardiac tissues from wild-type and Nox1-Nox2-Nox4 triple knockout mice, suggesting that it is not selective for NADPH-based ROS production; reacts with hydrogen peroxide without generating free radical intermediates; a fluorescent chloride-sensitive indicator, with its fluorescence being quenched by chloride (ex/em = 455/505 nm, respectively)
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Cayman Chemical ANTIBODY AG-1295 1mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A quinoxaline-type tyrphostin that acts as a potent and selective inhibitor of PDGF receptor kinase in vitro and in Swiss 3T3 cells (IC50s range from 0.3-1 µM); inhibits PDGF-stimulated DNA synthesis (IC50 = 2.5 µM) without affecting activity of the EGF receptor
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Cayman Chemical DobutamInhydrochlorIde 5mg
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A β-adrenergic receptor agonist with potent positive inotropic effects in vivo; strongest effects on β1 receptors, with lesser but significant β2 receptor activation and only weak α1 receptor actions; strongly increases cardiac contractility
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Cayman Chemical galacto-DapaglIflozIn 5mg
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A potent inhibitor of human SGLT2 that is 1,000-fold less potent at human SGLT1 (Ki values are 2 and 25,000 nM, respectively); dissociates from hSGLT2 more slowly than from hSGLT1 (half-time off rates are 19 and 0.9 seconds, respectively)
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Cayman Chemical ANTIBODY UNC0379 25mg
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A selective inhibitor of the lysine methyltransferase SET8 (IC50 = 7.3 µM; Kd = 18.3 µM)
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Cayman Chemical ANTIBODY ML-228 50mg
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An activator of the HIF signaling pathway, as demonstrated by HRE reporter assay (EC50 = 1.2 µM), HIF-1α nuclear translocation assay (EC50 = 1.3 µM), and increased VEGF expression (EC50 = 1.6 µM); activity is blocked by excess iron, suggesting that ML-228 can chelate iron
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Enterprise Technology Solutions HP 91, (c9461a) Magenta/yellow Printhead
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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HP 91, (c9461a) Magenta/yellow Printhead
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Cayman Chemical ANTIBODY CCT137690 5mg
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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A potent inhibitor of Aurora kinases (IC50s = 15, 25 and 19 nM for Aurora A, B, and C, respectively); also inhibits FLT3 as well as the constitutively active FLT3-ITD form (IC50s = 1.2 and 4.9 nM, respectively); orally bioavailable, inhibiting the growth of SW620 colon carcinoma xenografts in mice
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WEBER SCIENTIFIC 100 YM PEEL PLATES 2X50 100/PK
NC3443778 100 YM PEEL PLATES 2X50 100/PK
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Abcam HPI-1, hedgehog signaling inhibitor, 5MG
MW 463.5 Da, Purity >98%. Potent hedgehog signaling inhibitor (IC₅₀ values are 1.5 (Shh), 1.5 (SAG), 4 (Gli2) and 6 μM (Gli1)). Antitumor agent. Active in vivo and in vitro..
The product is subject to the following: Abcam Restricted Use Statement
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